
Restricted use pesticides (RUP) are for retail sale to, and use by, only certified applicators or persons under their direct supervision and only for those purposes covered by the applicator's certification. When a pesticide is classified as restricted, the label will state "Restricted Use Pesticide" at the top of the front panel. Below this heading may be a statement describing the reason for the restricted classification (Figure 1). There are various reasons which are determined by the U.S. Environmental Protection Agency (EPA) why a particular pesticide is classified as restricted. These criteria involve the EPAs determination that the pesticide may be hazardous to human health or to the environment even when used according to the label.
Some states, including Florida, adhere to the EPAs Federal listing for determining those pesticide active ingredients that are classified as “restricted.” Other states may require that certain other active ingredients not listed on the Federal list be classified as “restricted” in their states due to local conditions, generally related to environmental concerns. Although some restricted use active ingredients may be federally registered, they may not have a Florida registration.
Reasons for RUP classification that are given in this guide may include terminology such as:
Fetotoxicity – adverse effects on the fetus;
Mutagenicity – causes genetic changes in the organism which may or may not be passed on to its next generation;
Oncogenicity – causes tumors, but not necessarily malignant, and
Teratogenicity – causes birth defects.
The pesticide's label is the last word on use, regardless of its classification as a general use or a restricted use pesticide.
This guide provides a listing of common names of pesticides determined to be classified as restricted use by the EPA and registered for use in Florida (Table 1). With each entry, formulations that are regarded as restricted, their uses and the reason(s), if given, for their restricted classification are is cited. Common names of pesticides that have had their registrations cancelled or those whose restricted status is no longer in effect are shown in Table 2. Be aware that the listing is slightly modified, generally on an annual basis. For updated listings of Federal restricted use pesticides, see: http://www.epa.gov/opprd001/rup/.
Federally-restricted pesticides registered in Florida.
Pesticide common name |
Specific formulations |
Specific uses |
Criteria for RUP |
Acetochlor |
Emulsifiable concentrate |
Field corn, popcorn, forage/feeder corn |
Ground and surface water concerns |
Acrolein |
As sole active ingredient |
All uses |
Human inhalation hazard, adverse effects on avian and aquatic organisms |
Alachlor |
All formulations |
All uses |
Oncogenic potential |
Aldicarb |
As sole active ingredient and in combination with other actives; all granular formulations |
All uses |
Accident history |
Aluminum phosphide |
As sole active ingredient |
All uses |
Human inhalation hazard |
Amitraz |
All formulations |
Pears |
Possible oncogenicity |
Amitrole |
All formulations |
All uses except homeowner |
Oncogenic potential |
Arsenic acide |
All formulations except brush-on |
All dessicant uses; all wood preservative uses |
Oncogenicity, mutagenicity and repro/fetotoxicity |
Arsenic pentoxide |
All formulations |
Wood preservative uses |
Potential oncogenicity, mutagenicity, repro/fetotoxicity |
Atrazine |
All manufacturing and end use |
Agricultural and industrial uses |
Ground water contamination potential; worker exposure concerns |
Avermectin |
Emulsifiable concentrate |
Cotton and citrus |
Toxic to fish, mammals and aquatic organisms |
Avitrol |
All formulations |
All uses |
Hazard to fish and non-target birds |
Azinphos-methyl |
All liquids with greater than 13.5% concentration; others on a case-by-case basis |
All uses |
Human inhalation hazard, acute toxicity, hazard to avian, aquatic and mammalian species |
Bendiocarb |
Granular and wettable powder |
Turf |
Toxicity to aquatic and avian species |
Bifenthrin |
Emulsifiable concentrate |
Cotton |
Toxic to fish and aquatic organisms |
Bis(tributyltin)oxide |
Solution – ready to use |
Antifouling paint |
Toxic to aquatic organisms including shellfish |
Carbofuran |
All formulations except pellets and tablets |
All uses |
Acute inhalation toxicity; avian toxicity (granular) |
Chlorophacinone |
Tracking powder, dust and ready to use 0.2% (EPA Reg. Nos. 7173-113 and 7173-172 |
Inside buildings |
Human hazard, potential for food contamination, possible inhalation hazard |
Chloropicrin |
All formulations greater than 2% and all formulations (rodent control) |
All uses (greater than 2% including rodent control) |
Acute inhalation toxicity, hazard to non-target organisms |
Chlorpyrifos |
Emulsifiable concentrate |
Agricultural uses |
Avian and aquatic toxicity |
Chromic acid |
All formulations except brush-on |
All wood preservative |
Oncogenicity, mutagenicity, teratogenicity and fetotoxic effects |
Clofentezine |
All formulations |
All uses |
Additional data required to remove the restriction |
Coal tar |
Solution – ready to use |
Wood preservative |
Oncogenicity and mutagenicity |
Coal tar creosote |
All formulations |
Wood preservative |
Possible oncogenic and mutagenic effects |
Coumaphos |
Flowable concentrate |
Indoor food and indoor nonfood |
Acute oral toxicity hazards |
Cube resins other than rotenone |
Emulsifiable concentrate |
Small fruits, currants, certain berries |
Chronic eye and inhalation effects |
Cyfluthrin |
25% Emulsifiable concentrate |
Agricultural |
Acute toxicity to applicators, fish and other aquatic organisms |
Cyhalothrin |
Emulsifiable concentrate |
Cotton |
Environmental data requirements |
Cypermethrin |
All formulations |
All agricultural crops |
Oncogenicity, hazard to non-target organisms |
Deltamethrin |
Emulsifiable concentrate |
Cotton |
High toxicity to aquatic organisms |
Diazinon |
Granular, emulsifiable concentrate and wettable powders |
Small fruits and certain berries |
Avian and aquatic toxicity |
Dichlobenil |
2,6-dichlorobenzonitrile |
Terrestrial |
Conditional |
Dichloropropene |
All formulations (94% liquid concentrate is the only formulation) |
All uses |
Probable human carcinogen, oncogenic, acutely toxic by oral and inhalation routes |
Diclofop methyl |
All formulations |
All uses |
Oncogenicity |
Dicrotophos |
All liquid formulations 8% and greater |
All uses |
Acute dermal toxicity, residue effects on avian species |
Diflubenzuron |
Wettable powders |
All uses |
Hazard to wildlife |
Disulfoton |
All ECs 65% and greater, all ECs and concentrate solutions 21% and greater with fensulfothion 43% and greater, all ECs 32% and greater in combination with 32% fensulfothion and greater |
All uses, commercial seed treatment (non-aqueous solution 95% and greater). |
Acute dermal toxicity, inhalation hazard |
Emamectin benzoate |
4-epimethlyamino-4-deoxykavermectin BLA and B1b benzoates |
Insecticide, miticide |
Toxicity to fish |
Esfenvalerate |
66% emulsible concentrate |
Insecticide |
Toxicity to fish and aquatic organisms |
Ethoprop |
Emulsifiable concentrates 40% and greater (aquatic uses); all uses (granular and fertilizer formulations |
Aquatic uses (ECs 40% or greater); all uses (granular and fertilizer formulations) |
Acute dermal toxicity |
Fenamiphos |
Emulsifiable concentrates 35% and greater |
All uses |
Acute dermal toxicity, avian acute oral toxicity, acute inhalation toxicity |
Fenbutatin-oxide |
Wettable powder |
Grapes |
Very high toxicity to aquatic organisms |
Fenpropathrin |
2.4 emulsifiable concentrate spray |
Agricultural uses |
Environmental concerns: toxic to fish and aquatic organisms |
Fenthion |
Emulsifiable concentrate |
Mosquitocide |
Very high acute toxicity to birds, fish and aquatic invertebrates |
Fipronil |
All formulations |
Insecticide/miticide |
Conditional amended |
Hydrogen cyanamide |
50% active ingredient |
Desert grown grapes Potato |
Corrosive effects to skin and eyes |
Lambda-cyhalothrin |
All formulations |
All uses |
Toxicity to fish and aquatic invertebrates |
Magnesium phosphide |
All formulations |
All uses |
Inhalation hazard |
Methamidophos |
Liquid formulations 40% and greater, dust formulations 2.5% and greater |
All uses |
Acute dermal toxicity, residue effects on avian species |
Methidathion |
All formulations |
All uses except nursery stock, safflower and sunflower |
Residue effects on avian species |
Methiocarb |
All formulations |
Outdoor commercial and agricultural uses |
Possible hazard to avian, fish and other aquatic organisms |
Methomyl |
As sole active ingredient in 1 to 2.5% baits (except 1% fly bait), all concentrate solution formulations and 90% wettable powder formulations (not in water soluble bags) |
Nondomestic outdoor and all other registered uses (agricultural crops, ornamentals and turf) |
Residue effects on mammalian species, other hazards – accident history |
Methyl bromide |
All formulations |
All uses |
Acute toxicity and accident history |
Methyl isothiocyanate |
Solution – ready to use |
Fungicide for wood, wood preservative |
Exceeds classification criteria of 40 CFR 152.170 |
Methyl parathion |
All formulations |
All uses |
Residue effects on mammalian and avian species, hazard to bees, acute dermal toxicity |
Niclosamide |
All wettable powders 70% and greater |
All uses |
Acute inhalation toxicity, effects on aquatic organisms |
Nicotine |
Liquid and dry formulations 14% and greater (greenhouse); all formulations (cranberries) |
Greenhouse applications, all applications to cranberries |
Acute inhalation toxicity, effects on aquatic organisms |
Nitrogen, liquid |
Solution – ready to use |
Termiticide |
Highly corrosive upon contact with skin or eyes |
Oxamyl |
Liquid formulations, granular on a case-by-case basis |
All uses |
Acute oral toxicity, acute inhalation toxicity, avian oral toxicity |
Oxydemeton methyl |
All products |
All uses |
Reproductive effects |
Paraquat |
All formulations and concentrations except certain mixtures – see label |
All uses |
Human toxicological data, other hazards – use and accident history |
Pentachlorophenol |
All formulations |
Wood preservative uses |
Possible oncogenic, teratogenic and fetoxic effects |
Pentachlorophenol, Sodium S |
All formulations |
Wood preservative uses |
Possible oncogenic, mutagenic and/or fetotoxic effects |
Permethrin |
All formulations |
Agricultural crop uses |
Highly toxic to aquatic organisms, oncogenicity |
Phorate |
Liquid formulations 65% and greater (all uses); all granular formulations (rice) |
All uses (65% and greater); granular formulations (rice) |
Acute oral and dermal toxicity for granulars, residue effects on avian and mammalian species (foliar application of liquid formulation only), effects on aquatic organisms |
Piperonyl butoxide |
Emulsifiable concentrate |
Small fruits, certain berries, currants |
Not specified |
Profenofos |
Emulsifiable concentrate 59.4%, EPA Reg. Nos. 100-599 and 100-669 |
Cotton |
Corrosive to eyes |
Pronamide |
All 50% wettable powders |
All uses |
Oncogenicity |
Propanoic acid |
Emulsifiable concentrate |
Wheat, rice, edible chrysanthemum, cotton, clover, alfalfa, wheat-grass, sideoats grama, little bluestem |
Not specified |
Pyrethrins |
Emulsifiable concentrate |
No uses listed |
Chronic eye effects |
Resmethrin |
All formulations |
Mosquito abatement and pest control treatments at nonagricultural sites |
Acute fish toxicity |
Rotenone |
2.5/5.0 EC, 5.0% +20.0% wettable powder |
Fish toxicant |
Chronic eye and inhalation effects |
Simazine |
Emulsifiable concentrate |
Grapes and certain berries |
Not specified |
Sodium cyanide |
All capsules and ball formulations |
All uses |
Human inhalation hazard, hazard to non-target species |
Sodium dichromate |
All wood preservative formulations except brush-on |
Wood preservative uses |
Oncogenicity, mutagenicity, teratogenicity and fetotoxocity |
Sodium fluoroacetate |
All solutions and dry baits |
All uses |
Acute oral toxicity, hazard to non-target organisms, use and accident history |
Sodium hydroxide |
Ready to use solution |
Control tree roots in sewage systems |
Acute toxicity; eye, inhalation and dermal hazard |
Sodium methyldithiocarbamate |
32.7% anhydrous |
Soil fumigant to control soilborne pests of ornamental, food and fiber crops and for root control in sewage systems |
Dermal toxicity and teratogenicity. Acute toxicity of metam sodium and its intended use in controlling sewer root growth |
Strychnine |
Dry baits, pellets and powder formulations – see specific labels |
Formulations greater than 0.5%: all uses. All formulations: all uses calling for burrow builders. Formulations less than 0.5%: all uses except below-ground hand application. |
Acute oral toxicity hazard to non-target avian species; use and accident history |
Sulfotepp |
Sprays and smoke generators |
All uses |
Inhalation hazard to humans |
Sulfuric acid |
Solution – ready to use |
Potato vine desiccant |
Extremely corrosive – acute toxicity to humans |
Sulfuryl fluoride |
All formulations |
All uses |
Acute inhalation hazard and possible acute toxicity hazard in humans |
Tefluthrin |
Granular formulations |
Corn grown for seed |
Environmental concerns Toxicity to fish and aquatic organisms |
Terbufos |
Granular formulations 15% and greater |
All uses |
Residue effects on avian species; acute oral and dermal toxicity and risks to aquatic organisms and other wildlife from runoff |
TFM |
Impregnated material |
Aquatic pest control |
Complexity in use- requires specialized training, equipment and clothing |
Tralomethrin |
All formulations |
All agricultural crop uses |
Toxicity to aquatic organisms |
Tributyltin fluoride |
Solution – ready to use |
Antifouling paint |
Toxicity to aquatic organisms including shellfish |
Tributyltin methacrylate |
Solution – ready to use |
Antifouling paint |
Toxicity to aquatic organisms |
Triisopropranolamine |
Emulsifiable concentrate |
All uses |
Hazard to non-target organisms, specifically plants both crop and noncrop |
Triphenyltin hydroxide |
All formulations |
All uses |
Possible mutagenic effects |
Zinc phosphide |
All dry formulations 60% and greater; all bait formulations; all dry formulations 10% and greater |
All uses – non-domestic outdoor uses (other than 1-2% formulation in/around buildings); domestic uses |
Hazard to non-target organisms, acute oral toxicity, acute inhalation toxicity |
Pesticides deleted from the restricted use list because of cancellation.
Pesticide common name |
Trade name |
Pesticide type |
Acrylonitrile |
Acritet 34-66 |
Fumigant, insecticide |
Allyl alcohol |
Weed Seed Killer |
Herbicide |
Alpha-chlorohydrin |
Epibloc |
Rodenticide |
Brodifacoum |
Talon G |
Rodenticide |
Butylate |
Sutazine |
Herbicide |
Cadmium chloride |
Caddy |
Fungicide |
Calcium cyanide |
A-Dust, G-Fumigant |
Insecticide |
Carbon dioxide |
Makr carbon dioxide |
Fumigant |
Carbon tetrachloride |
Dowfume 75, Vulcan Formula 72 |
Fumigant |
Chlordane |
Chlordane |
Termiticide |
Chlordimeform |
Galecron, Fundal |
Insecticide, miticide |
Chlorfenvinphos |
Poultry Premise Larvicide |
Insecticide |
Chlorobenzilate |
Acaraben, Benz-o-chlor, Benzilan |
Insecticide |
Chlorothalonil |
Dacobre |
Fungicide |
Copper oxychloride |
Dacobre DG |
Fungicide, bactericide |
Creosote |
BL Coal tar creosote (non-pressure) |
Wood preservative |
Cupric oxide |
Chapman CCA-50 |
Fungicide |
Cyanazine |
Bladex |
Herbicide |
Cycloheximide |
Acti-Aid |
Fumigant, insecticide |
DBCP |
Nematocide EM or Solution |
Fumigant |
Demeton |
Systox 2, Systox 6, Demox, Stemite |
Insecticide |
Diallate |
Avadex |
Herbicide |
Diphacinone |
Gold Crest Tracking Powder |
Rodenticide |
Dodemorph |
Milban |
Fungicide |
E-mevinphos |
Duraphos, Phosdrin |
Insecticide |
Endrin |
Endrin |
Insecticide |
EPN |
EPN, Barricade, Powertox, MEPN, Budmor, Raider, Veto, others |
Insecticide |
Ethylene dibromide |
TRI-X Garment Fumigant, Infuco Dibrome |
Fumigant |
Fensulfothion |
Dasanit, BIG-D Granules |
Insecticide |
Flucythrinate |
Pay Off, AASTAR |
Insecticide |
Fluoroacetamide |
Fluoroacetamide/1080 |
Rodenticide |
Fluvalinate |
Mavrik, Spur |
Insecticide |
Fonofos |
Dyfonate |
Insecticide |
Hydrocyanic acid |
HCN |
Fumigant |
Isazofos |
Triumph 4E |
Insecticide |
Isofenphos |
Pryfon 6, Amaze 6 |
Termiticide |
Monocrotophos |
Azodrin, DPHMC 5, Chiles Go-Better |
Insecticide |
Phosacetim |
Gophacide, Gopher-Trol, others |
Rodenticide |
Phosalone |
Zolone |
Insecticide |
Phosphamidon |
Phosphamidon 8 |
Insecticide |
Potassium pentachlorophenate |
Permatox 180 or 182 |
Wood preservative |
Sodium arsenate |
Sodium arsenate, Osmosalts |
Wood preservative |
Sodium pyroarsenate |
Wolmans Salts CCA-Type B |
Wood preservative |
TEPP |
Miller Kilmite-40 |
Insecticide |
Tergitrol |
Compound PA-14 |
Bird control |
Toxaphene |
Toxaphene |
Insecticide |
Z-mevinphos |
Phosdrin, Duraphos |
Insecticide |
This document is PI-36, one of a series of the Pesticide Information Office, Florida Cooperative Extension Service, Institute of Food and Agricultural Sciences, University of Florida. Published March 2005. Revised July 2006. Visit the EDIS Web Site at http://edis.ifas.ufl.edu.
Frederick M. Fishel, Associate Professor, Agronomy Department, and Director, Pesticide Information Office; Florida Cooperative Extension Service, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL 32611.
The use of trade names in this publication is solely for the purpose of providing specific information. UF/IFAS does not guarantee or warranty the products named, and references to them in this publication does not signify our approval to the exclusion of other products of suitable composition.
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contact your county Cooperative Extension service.
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