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Publication #FSHN10-05

The Cause of Trichinosis and Its Prevention Through Safe Food Handling Practices1

Alina Balaguero and Keith R. Schneider2

This is one in a series of fact sheets discussing common foodborne pathogens of interest to food handlers, processors, and retailers.

What Is Trichinosis?

Trichinosis is an infection caused by roundworms in the genus Trichinella, with infection resulting primarily from food sources. Illness occurs as a result of ingesting Trichinella larvae from undercooked meat, typically pork, and the resultant activity of adult worms in the intestines as well as larvae encysted in host tissue (Crompton and Savioli 2006).

What Is Trichinella?

Trichinella is a genus of roundworms that are unique in their extremely low degree of host specificity; they can infect a wide range of mammals and some birds. The main two species of Trichinella associated with human infection in the United States are T. spiralis and T. murrelli, though T. spiralis is responsible for the most human infections. The intermediate hosts of most concern to humans are swine (Despommier 2005).

Incidence of Trichinosis

According to the most recent data from the Centers for Disease Control and Prevention (CDC), there were 66 reported cases of trichinosis for the years 2002–2007. Of these 66 cases, the consumption of pork was responsible for 43; the rest were caused by the consumption of improperly cooked wild game or unknown sources (CDC 2009). Other animals known to carry T. spiralis include horses, rats, foxes, wolves, bears, seals, and wild boars (WSDOH 2011).

How Do Humans Get Infected withTrichinella?

When a human consumes raw or undercooked meat infected with Trichinella larvae, the ingested larvae establish residency in the small intestine, where they typically grow to maturity in less than a week (Redman 2007). Adult worms within the small intestine will mate, and the females will give birth to live larvae that will subsequently penetrate the mucous membrane of the small intestine. Upon penetrating the mucous membrane, larvae can gain access to the bloodstream, the lymphatic system, or both.

Once in the bloodstream or lymphatic system, larvae can then travel to most areas of the human body. Larvae indiscriminately infect host cells, and can infect any type of tissue. However, larvae prefer to infect skeletal muscle cells, where they end up encysting themselves, thus allowing the disease to spread when that infected muscle tissue is consumed (Despommier 2005).

Disease and Onset Time of Trichinosis

Most damage to the body occurs during the invasion of extraintestinal host cells by larvae (which may invade and kill brain, kidney, liver, heart, and most other types of cells), or the encysting of larvae in skeletal muscle tissue (Despommier 2005). Symptoms associated with trichinae in the intestines can begin as early as 1–2 days following infection, and further symptoms associated with larvae colonizing extraintestinal tissue will occur between 2–8 weeks after ingestion of the contaminated food (CDC 2012).

What Are the Symptoms of Trichinosis?

The severity of symptoms is directly related to how many larvae are ingested, with a larger amount producing more symptoms of greater severity. If very few larvae are ingested, the patient may be completely asymptomatic, or may experience very general flu-like symptoms that may never be properly diagnosed (Despommier 2005). In more serious infections, the patient may initially experience nausea, vomiting, diarrhea, and muscle pain (CDC 2012), possibly followed by secondary diseases, such as neuro-trichinellosis, myocarditis, and dyspnea, if larvae migrate to brain, heart, or other vital tissues (Despommier 2005).

What Is the Treatment for Trichinosis?

Many antihelminthic drugs are available for use in the treatment of trichinosis, including albendazole and mebendazole (WSDOH 2011). The efficacy of treatment is dependent upon how soon the infection is caught and how severe the infection is. Some mild infections are never diagnosed or treated, but resolve themselves after several weeks (Despommier 2005).

Prevention of Trichinosis Before Slaughter

Trichinosis is spread to intermediate hosts such as pigs in the same way it is spread to humans: through food. Trichinella worms typically infect less than 0.2% of grain-fed hogs, but tend to infect hogs fed on uncooked garbage much more frequently (McWilliams 1974). If a hog is fed uncooked meat contaminated with Trichinella, that hog may become infected, leading to possible infections in humans who consume the meat from that hog. Because of the risks associated with uncooked garbage, all states in the United States are required to cook garbage thoroughly before it is fed to swine (McWilliams 1974). [See EDIS document AS143/AN143 Feeding Food Wastes to Swine at for more on the treatment of food waste intended for use as a source of feed for swine.]

Swine and other livestock should also be kept from eating the carcasses of dead animals, such as rats, that may have died on the premises and may also carry disease (CDC 2012). All swine should be adequately and responsibly fed to reduce their tendency to root for food sources that may be unsafe (Meyer and Brendemuhl 2003).

In addition to the proper feeding of hogs and cooking of garbage, certain methods of animal husbandry may be used to prevent trichinosis in livestock. One method is total isolation, in which domestic animals are raised entirely indoors, leaving little to no opportunity for parasitic infection. However, this method is not economically feasible for most domesticated animals, and it is likely to be considered by some as objectionable from a holistic point of view. Alternatively, the regular rotation or renovation of pastures may serve to limit the amount of exposure of swine to trichinae passed through the feces of other swine (Meyer and Brendemuhl 2003).

Many de-worming chemicals have been shown to safely control internal parasites in swine, as long as the manufacturer's instructions are strictly followed. Some of the most effective include Dichlorvos, Levamisole, and Pyrantel (Meyer and Brendemuhl 2003).

Government Inspection and Testing for Trichinosis

The USDA is responsible for verifying the wholesomeness of meats sold in the United States. However, trichinae are not typically discovered during USDA inspection due to their microscopic size, so no pork sold in the United States should be assumed to be safe from trichinae. The European Union (EU) tends to be more rigorous in its inspection of pork for trichinae, employing several techniques not typically used in the United States. Tests used by the EU include the following:

    • Compression method. In the compression method, samples from the diaphragms of hogs are tested for the presence of worms by being pressed between two glass slides and then examined with a microscope. This method has a sensitivity of about 3 larvae per gram of sample tissue (Gamble 2001).

    • Trichinoscopy. Trichinoscopy involves taking muscle samples from hogs after being slaughtered. Those samples are then magnified and projected onto a screen, allowing for constant visual surveillance for infected tissue (Cox 1982).

    • Pooled Sample Digestion Method. In the pooled sample digestion method, tissue samples are retrieved from areas of the hog which traditionally have high concentrations of larvae, and are digested using acidified pepsin, which releases the larvae from their capsules and allows them to be microscopically quantified (Gamble 2001).

Destruction and Prevention of Trichinae in Industry

To prevent cross-contamination of uninfected meat with infected meat, it is highly recommended that the equipment used to process meat, particularly grinders, be regularly cleaned and sanitized. This decreases the likelihood that infection from one source will subsequently contaminate another (CDC 2012).

Performed under very carefully controlled conditions, the food industry may attempt to destroy trichinae through curing and smoking, pickling, freezing, or cooking and canning (Dresser and Bellenir 1995). However, the International Commission on Trichinellosis (ICT) only recognizes three methods for reducing the number of larvae in meats to safe levels—freezing, irradiating, or cooking (ICT 2007).

Prevention of Trichinosis through Freezing

Trichinella can typically be inactivated through freezing at specific time/temperature intervals (Table 1). However, Trichinella found in many arctic animals are resistant to freezing and can survive as long as four years at -18°C (Kapel et al. 1999), suggesting that meat from arctic or Antarctic animals should be cooked rather than frozen to inactivate Trichinella. The following describes USDA's guidelines for commercial freezing of pork products.

  • After preparatory chilling to a temperature of 40°F or below, or preparatory freezing, all parts of the product must be subjected continuously to temperatures at or below those in Table 1, for the specified time (USDA 2001).

Table 1. 

Temperature °F

Group 1


Group 2











  • Group 1 includes products comprised of separate pieces not exceeding 6 inches in thickness, products arranged on separate racks with respective layers not exceeding 6 inches in thickness, products stored in crates or boxes not exceeding 6 inches in depth, or stored as solidly frozen blocks not exceeding 6 inches in thickness (USDA 2001).

  • Group 2 includes products in pieces, layers, or within containers, whose thicknesses are greater than 6 inches but less than 27 inches (USDA 2001).

Alternatively, the USDA allows the treatment of pork products to consist of commercial freeze drying or controlled freezing processes according to Table 2 (USDA 2001).

Table 2. 

Minimum Internal






















106 hours

82 hours

63 hours

48 hours

35 hours

22 hours

8 hours

½ hour

Prevention of Trichinosis through Irradiation

Irradiation has been used to inactivate trichinae in industry. Studies show that treatment of pork with 0.3 kGy of irradiation with Cobalt-60, or irradiation with high energy X-rays are completely effective against Trichinella (Gamble 2001). The ICT considers irradiation to be an effective method for reducing larvae in meat to levels safe for human consumption. The ICT finds that irradiation of products at 0.3 kGy effectively inactivates trichinae, but recommends that irradiation only be used on food that is packaged and sealed (ICT 2007).

Prevention of Trichinosis through Cooking Techniques

The following describes USDA's guidelines for commercial cooking of pork products:

  • One of the time and temperature combinations from Table 3 must be used in the heat treatment of all pork muscle tissue (USDA 2001).

Table 3. 

Minimum time and temperature combinations for the heat treatment of all pork muscle tissue, per USDA mandate

Minimum Internal



Time (min)










































  • If the product is not cured or fermented, the time to raise the product temperature from 60°F to 120°F should not take more than two hours (USDA 2001).

  • All parts of the product should be heated to the appropriate internal temperature. Products heated through submersion in water must remain submerged throughout the heating process (USDA 2001).

The following are effective home cooking guidelines and recommendations to protect against trichinosis:

  • Fresh pork, uncured pork chops greater than or equal to one inch in thickness, and cured picnic shoulders should be heated to an internal temperature of 170°F (McWilliams 1974).

  • The most effective method for cooking pork greater than 1 inch in thickness is the use of moist heat, such as in braising, as unpalatable damage to or burning of the surface of the meat may occur if an attempt is made to fry thick pork to the necessary internal temperature (McWilliams 1974).

  • All hams that have not been heated during processing should be cooked to an internal temperature of 165°F–170°F. Heat-cured hams and tenderized hams, which are only partially cooked during processing and are labeled "cook before eating," should be cooked to an internal temperature of 160°F. Those hams labeled "ready-to-eat" have been cooked to doneness during processing and may generally be cooked according to the preference of the consumer (McWilliams 1974).

  • While cooking meat, it is better to use a well-calibrated meat thermometer instead of a doneness timetable, as such timetables don't take into account the varying amounts of bone and fat in the product, which affect cooking time (McWilliams 1974).

  • Trichinae are not always killed by microwaving, smoking, curing, or drying (CDC 2012).


Centers for Disease Control and Prevention. 2009. Trichinellosis Surveillance - United States, 2002–2007. By S. Roy, A. Lopez, and P. Schantz. Morbidity and Mortality Weekly Report, 4 Dec. 2009.

Centers for Disease Control and Prevention. Division of Parasitic Diseases. Trichinosis. 2012. Web. Last accessed on 11 Jul. 2013.

Cox, F. E. G. Modern Parasitology a Textbook of Parasitology. Oxford: Blackwell Scientific, 1982.

Crompton, D. W. T., and L. Savioli. Handbook of Helminthiasis for Public Health. Null: CRC, 2006.

Despommier, D. D. Parasitic Diseases. 5th ed. North Mankato: Apple Trees Productions, LLC, 2005.

Dresser, P., and K. Bellenir. Food and Animal Borne Diseases Sourcebook. Vol. 7. Detroit, MI: Omnigraphics, 1995.

ICT Standards of Control Guidelines Committee. Recommendations on Methods for the Control of Trichinella in Domestic and Wild Animals Intended for Human Consumption. International Commission on Trichinellosis. 2007. Web. Last accessed on 11 Jul. 2013.

Kapel, C.M.O., Pozio, E., Sacchi, L., and P. Prestrud. 1999. Freeze tolerance, morphology, and RAPD-PCR identification of Trichinella native in naturally infected arctic foxes. J Parasitol 85:144-147.

McWilliams, M. Food Fundamentals. New York: Wiley, 1974.

Meyer, R. O., and J. H. Brendemuhl. Controlling Internal Parasites in Swine. Electronic Data Information Source - UF/IFAS Extension. 01 Apr. 2003. Web. Last accessed on 11 Jul. 2013.

Redman, N. Food Safety: A Reference Handbook. Santa Barbara, CA: Contemporary World Issues, 2007.

Washington State Department of Health. Trichinosis (Trichinellosis). Jan. 2011. Web. Last accessed on 11 Jul. 2013.

USDA. Food Safety Inspection Service. 9 CFR Ch. III (1–1–01 Edition) §318.10. Government Printing Office. 01Jan. 2001. Web. Last accessed on 11 Jul. 2013.

USDA. Trichinae. By H. R. Gamble. Animal and Plant Health Inspection Service, 18 Jan. 2001. Web. Last accessed on 11 Jul. 2013.



This document is FSHN10-05, one of a series of the Food Science and Human Nutrition Department, UF/IFAS Extension. Original publication date June 2010. Revised November 2013. Reviewed December 2016. Visit the EDIS website at


Alina Balaguero, student; and Keith R. Schneider, Ph.D., professor; Food Science and Human Nutrition Department, UF/IFAS Extension, Gainesville, FL 32611.

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