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Facts about Wildlife Diseases: SARS-CoV-2 in White-Tailed Deer

Samantha M. Wisely

What are SARS-CoV-2 and COVID-19?

Sudden acute respiratory syndrome coronavirus 2, or SARS-CoV-2, is the virus responsible for the global pandemic that began in late 2019. While SARS-CoV-2 is the name of the virus, coronavirus disease 2019 or COVID-19, is the name of the disease it causes. Prior to the SARS-CoV-2 pandemic, another coronavirus, SARS-CoV-1, almost became a pandemic in 2003. Both viruses are zoonotic, meaning that they can jump between animal species and people (Masters and Perlman 2013; Andersen et al. 2020).

SARS-CoV-2 is a member of the coronavirus family, which has hundreds of different virus species that cause respiratory and gastrointestinal disease in people, domestic species, and wildlife. Coronaviruses are responsible for a large proportion of common colds in people each winter, but other coronaviruses can cause severe illness, as we have seen with the global pandemic caused by SARS-CoV-2.

Can white-tailed deer get COVID-19?

Many coronaviruses can be transmitted across species, including the virus that causes COVID-19. Studies have shown that many mammals can become infected with SARS-CoV-2. There is growing evidence that people can transmit the virus to various species, including domestic cats (Chaintoutis et al. 2021), farmed mink (Molenaar et al. 2020), and dogs (Sit et al. 2020). Mink and cats are known to spread the virus within the species, for example from mink to mink. In some cases, like on mink farms, people have become infected from mink (Oude Munnink et al. 2021). Vaccines are being developed for multiple animal species to slow or prevent transmission of the virus from animal to animal or from animals to people (Murphy and Ly 2021).

Dr. Juan Campos Krauer
Figure 1. 
Credit: Dr. Juan Campos Krauer

Recently, a series of studies has demonstrated that white-tailed deer can become infected with SARS-CoV-2. Experimental infection of white-tailed deer with SARS-CoV-2 demonstrated that white-tailed deer are highly susceptible to infection, but they do not show signs of illness (Cool et al. 2021). Deer-to-deer transmission has been demonstrated experimentally (Palmer et al. 2021).

Studies have shown that wild white-tailed deer can also become infected. In northeast Ohio from January to March 2021, hunter-harvested deer had a SARS-CoV-2 infection prevalence of 35%. The genetic variant of the virus was the same as the variant that was peaking in people in northeast Ohio at the same time. Molecular epidemiological analysis of deer and people demonstrated transmission from people to deer and from deer to deer in the wild. Deer populations that were closest to urban centers had the highest prevalence of infection (Hale et al. 2021), but the exact mechanism of transmission is unknown. While respiratory aerosols are the most common route of exposure, contaminated wastewater has also been speculated as a route for people to pass the virus to deer (Bernard et al. 2021). It appears that wild white-tailed deer have been exposed to the virus in multiple parts of the United States. Deer from Illinois, Michigan, Pennsylvania, and New York had antibodies to SARS-CoV-2, which suggests they were exposed to the virus (Chandler et al. 2021). Since the first discovery of the virus in deer, routine pathogen surveillance of white-tailed deer in Oklahoma (Ogle 2021) and Quebec, Canada (Agance France Presse 2021), have found the virus in wild white-tailed deer.

Can people get COVID-19 from deer?

As of December 2021, viral transmission from deer to people has not been demonstrated. Although this virus has previously been demonstrated to jump from various animal species to people, the risk to most people is very low. According to the Centers for Disease Control and Prevention COVID-19 guidelines (CDC 2021), there are 3 categories of risk for people to contract COVID-19 from wildlife depending on their behavior or occupation.

  1. The general public:

Most people fall into this category. General precautions should be taken for deer as for all wildlife.

  • Always keep a safe distance between yourself and wildlife.
  • Do not feed wildlife or touch wildlife droppings.
  • Keep pets away from wildlife.
  • Always wash your hands after playing or working outside.
  • Never handle dead or sick animals; contact your state wildlife agency instead.
  • Leave young animals alone. Parents are often hiding close by.

2. Hunters:

There is no evidence that people can contract COVID-19 from harvested deer meat, either while preparing or eating it. Hunters should always follow these best management practices to avoid getting sick from wildlife:

  • Do not allow contact between wildlife and pets or hunting dogs.
  • Do not harvest animals that appear sick or are found dead.
  • Keep game meat cool and clean.
  • When field dressing game meat:
    • Wear gloves.
    • Do not eat, drink or smoke.
    • Avoid cutting through the backbone and spinal tissues; avoid eating the brain.
    • Wash your hands, cutting surfaces and cutting utensils thoroughly when you are finished.
    • Consider wearing a mask if you are at an elevated risk for complications from COVID-19.
  • Cook your meat thoroughly (an internal temperature of 165oF or higher).

3. Deer farmers and wildlife professionals who will be in close proximity to white-tailed deer:

Activities that bring you in close contact with live animals increase your risk of contracting COVID-19 via respiratory aerosols. If you are in close contact with white-tailed deer, and/or if you are at an elevated risk for complications due to COVID-19, consider the following precautions:

  • Get vaccinated and/or boosted against COVID-19.
  • Wear a mask, eye protection and gloves when handling live deer.

For the latest information on CDC guidelines for COVID-19 in wildlife, visit this CDC website:

Agance France Presse. 2021. “Covid Detected In 3 White-Tailed Deer, Confirms Canada.” December 2, 2021.

Andersen, Kristian G., Andrew Rambaut, W. Ian Lipkin, Edward C. Holmes, and Robert F. Garry. 2020. “The Proximal Origin of SARS-CoV-2.” Nature Medicine 26 (4): 450–52.

Bernard, Kay, Angela Davis, Ian M. Simpson, Vanessa L. Hale, Jiyoung Lee, and Ryan J. Winston. 2021. “Detection of SARS-CoV-2 in Urban Stormwater: An Environmental Reservoir and Potential Interface between Human and Animal Sources.” The Science of the Total Environment October, 151046.

CDC. 2021. “Reducing the Risk of SARS-CoV-2 Spreading between People and Wildlife.” CDC: Healthy Pets, Healthy People. November 22, 2021.

Chaintoutis, Serafeim C., Victoria I. Siarkou, Mathios E. Mylonakis, George M. Kazakos, Panagiota-Nefeli Skeva, Maria Bampali, Marios Dimitriou, et al. 2021. “Limited Cross-Species Transmission and Absence of Mutations Associated with SARS-CoV-2 Adaptation in Cats: A Case Study of Infection in a Small Household Setting.” Transboundary and Emerging Diseases, no. tbed.14132 (April).

Chandler, Jeffrey C., Sarah N. Bevins, Jeremy W. Ellis, Timothy J. Linder, Rachel M. Tell, Melinda Jenkins-Moore, J. Jeffrey Root, et al. 2021. “SARS-CoV-2 Exposure in Wild White-Tailed Deer (Odocoileus virginianus).” Proceedings of the National Academy of Sciences of the United States of America 118(47).

Cool, Konner, Natasha N. Gaudreault, Igor Morozov, Jessie D. Trujillo, David A. Meekins, Chester McDowell, Mariano Carossino, et al. 2021. “Infection and Transmission of Ancestral SARS-CoV-2 and Its Alpha Variant in Pregnant White-Tailed Deer.” Emerging Microbes & Infections November, 1–39.

Hale, Vanessa L., Patricia M. Dennis, Dillon S. McBride, Jaqueline M. Nolting, Christopher Madden, Devra Huey, Margot Ehrlich, et al. 2021. “SARS-CoV-2 Infection in Free-Ranging White-Tailed Deer ( Odocoileus virginianus ).” BioRxiv : The Preprint Server for Biology, November.

Masters, P. S., and S. Perlman. 2013. “Coronaviridae." Fields Virology. Edited by D. M. Knipe and P. M. Howley. Lippincott Williams & Wilkins, Philadelphia. Vol. 1, 825–858.

Molenaar, Robert Jan, Sandra Vreman, Renate W. Hakze-van der Honing, Rob Zwart, Jan de Rond, Eefke Weesendorp, Lidwien A. M. Smit, et al. 2020. “Clinical and Pathological Findings in SARS-CoV-2 Disease Outbreaks in Farmed Mink (Neovison Vison).” Veterinary Pathology 57 (5): 653–57.

Murphy, Hannah L., and Hinh Ly. 2021. “Understanding the Prevalence of SARS-CoV-2 (COVID-19) Exposure in Companion, Captive, Wild, and Farmed Animals.” Virulence 12 (1): 2777–86.

Ogle, Katie. 2021. “People Likely Can’t Get COVID-19 from Eating Meat from Deer That Had Coronavirus, Oklahoma State University Wildlife Expert Says.” KFOR Oklahoma City, November 12, 2021.

Oude Munnink, Bas B., Reina S. Sikkema, David F. Nieuwenhuijse, Robert Jan Molenaar, Emmanuelle Munger, Richard Molenkamp, Arco van der Spek, et al. 2021. “Transmission of SARS-CoV-2 on Mink Farms between Humans and Mink and Back to Humans.” Science 371 (6525): 172–77.

Palmer, Mitchell V., Mathias Martins, Shollie Falkenberg, Alexandra Buckley, Leonardo C. Caserta, Patrick K. Mitchell, Eric D. Cassmann, et al. 2021. “Susceptibility of White-Tailed Deer (Odocoileus virginianus) to SARS-CoV-2.” Journal of Virology, March.

Sit, Thomas H. C., Christopher J. Brackman, Sin Ming Ip, Karina W. S. Tam, Pierra Y. T. Law, Esther M. W. To, Veronica Y. T. Yu, et al. 2020. “Infection of Dogs with SARS-CoV-2.” Nature 586 (7831): 776–78.

Peer Reviewed

Publication #WEC445

Release Date:January 7, 2022

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Wisely, Samantha M.


University of Florida

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About this Publication

This document is WEC-445, one of a series of the Wildlife Ecology and Conservation Department, UF/IFAS Extension. Original publication January 2022. Visit the EDIS website at for the currently supported version of this publication.

About the Authors

Samantha M. Wisely, professor of Wildlife Ecology, Department of Wildlife Ecology and Conservation, UF/IFAS Extension, Gainesville, FL 32611.


  • Samantha Wisely